Spider-Man’s 10 Most Powerful Villains Ranked

In a thrilling leap to Disney+, our familiar neighborhood web-slinger, Spider-Man, debuts with a double premiere. Kicking off Marvel’s expansive 2025 lineup, “Spider-Man from Our Neighborhood” offers a fresh perspective on the beloved hero’s origin tale. By skillfully blending elements that resonate with the MCU version while infusing their unique touch, this adaptation presents an innovative twist on the classic storyline. It’s not exactly Marvel’s “What If…?” but it certainly feels like a captivating exploration of the question, “What if Spider-Man were different?

In the initial two installments of “Your Friendly Neighborhood Spidey,” you’ll find a treasure trove of Easter eggs and nods to Marvel Comics, previous versions of Spider-Man, and the Marvel Cinematic Universe. The opening theme song, which encapsulates various Spider-Man eras, is just one example. Additionally, numerous characters from across the Marvel Universe make up the supporting cast, offering delightful references for fans while potentially hinting at future plot directions. Here’s a rundown of the most prominent Easter eggs and references spotted in the first two episodes of “Your Friendly Neighborhood Spider-Man.

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Mirroring ‘Captain America: Civil War’

Originally titled “Spider-Man: Freshman Year,” the concept of “Your Friendly Neighborhood Spider-Man” initially centered around a less-explored phase in Peter Parker’s backstory, prior to the occurrences of “Captain America: Civil War.” However, the series presents an intriguing twist: this timeframe is not our familiar reality, but rather an alternate timeline where instead of Tony Stark, it is Norman Osborn who recruits Peter Parker.

The series underwent a transformation into “Your Friendly Neighborhood Spider-Man“, starting in an alternate timeline because of the way Peter Parker acquires his spider bite. However, this episode shares many similarities with Captain America: Civil War, as it begins with a title card saying “Queens” over Peter Parker’s apartment complex, much like his debut in the Marvel Cinematic Universe. The closing scene of Episode 1 closely replicates key moments from the original, including the use of “Left Hand Free” by alt-J and depicting Peter Parker discovering a DVD player. But instead of Tony Stark approaching him with an offer, it is now Norman Osborn who extends a job proposal.

Instead of Tony Stark serving as a mentor potentially causing disagreement among fans, it’s downright chilling to consider Norman Osborn stepping into the role, especially since he’s infamous for being Spider-Man’s primary adversary, The Green Goblin.

Uncle Ben in ‘Your Friendly Neighborhood Spider-Man’

In a universe distinct from the Marvel Cinematic Universe but bearing striking similarities, the storyline of Spider-Man unfolds. Despite their differences, certain aspects of Peter Parker’s life could align between these two realms. The most significant shared point revolves around the destiny of Uncle Ben – a common thread that may hold true in both worlds.

In the Marvel Cinematic Universe movies, Uncle Ben wasn’t portrayed because by the time Spider-Man: Homecoming was released in 2017, viewers had already watched both Spider-Man and The Amazing Spider-Man deal with his death. In fact, none of the MCU Spider-Man films mentioned Uncle Ben by name, but they did refer to him indirectly in Spider-Man: Homecoming through a difficult situation Aunt May was going through, and later in Spider-Man: Far From Home when Peter used Uncle Ben’s luggage. In the latest movie, Your Friendly Neighborhood Spider-Man directly acknowledges Uncle Ben’s death before the events of the series unfolded.

In contrast to traditional Spider-Man lore, in this version, Uncle Ben dies after the spider bites Peter Parker instead of following his death prompting Peter to become Spider-Man due to his regret over not stopping a burglar who later kills Ben. This change significantly alters the reasons behind Peter Parker’s transformation into Spider-Man and the lessons he learns about responsibility, as “with great power comes great responsibility” may no longer be directly connected to Ben’s death in these adaptations.

Doctor Strange and Venom… From Across the Multiverse?

In a unique twist on the classic Spider-Man narrative, we find that instead of being bitten by a radioactive spider in a field trip or lab setting, our hero encounters the transformative bite during an epic battle. This isn’t just any fight; it’s a clash between Doctor Strange and a Venom-esque symbiote. The appearance of this Venom-like creature marks a significant event, as Venom is one of Spider-Man’s most famous adversaries, yet not traditionally associated with his origin story. In this version, however, the roles are reversed, with Venom now linked to Spider-Man’s origins rather than the other way around.

Including Doctor Strange in the movie serves as a delightful nod to his origins, co-created by Stan Lee and Steve Ditko, who also brought Spider-Man to life. Interestingly, Doctor Strange was featured in ‘Spider-Man: No Way Home’, and director Sam Raimi directed both the original ‘Spider-Man’ trilogy and ‘Doctor Strange in the Multiverse of Madness’. This suggests that his appearance might be a multi-layered reference, leading us to wonder about his origins or if he hails from this particular universe.

In the storyline that resembles the Marvel Cinematic Universe, it appears that our friendly neighborhood Spider-Man exists within a timeline where significant events like Doctor Strange’s fight with Venom differ from those in the MCU. According to The Marvel Cinematic Universe: An Official Timeline, Doctor Strange suffered his accident in February 2016, which precedes the summer/fall of 2015 when this fight took place. This suggests that the Doctor Strange we see in this universe might be a variant from another dimension.

Is it possible that the character played by Benedict Cumberbatch in the Marvel Cinematic Universe, following his confrontation with a Venom-like creature, could be part of a storyline post-“Doctor Strange in the Multiverse of Madness”? The Venom entity Doctor Strange may face seems to be connected to the symbiotes from “Venom: Let There Be Carnage,” and this upcoming series might serve as a bridge between these two distinct live-action Marvel Multiverse tales. If so, it would certainly add an exciting twist to movies like “Madame Web.” With Benedict Cumberbatch recently hinting at not being in “Avengers: Endgame,” this could potentially be the MCU’s Doctor Strange engaging with multiverse threats such as Venom.

Infinity War. Since this animated Doctor Strange possesses it, it might not be the same character from the MCU. It’s possible that the Doctor Strange in this story could be a different time period or even a future season of the MCU series. Similarly, the Venom that Doctor Strange is fighting could indicate a potential new direction for the MCU series.

It appears the Venom symbiote dons a large collar, possibly indicating that Kraven the Hunter – known adversary from the comics like “Spider-Man: Life Story” – may have control over the Venom symbiote suit. This could also foreshadow Peter Parker’s future struggle with being possessed by the Venom symbiote, with Doctor Strange stepping in to help him regain freedom. Given that “Your Friendly Neighborhood Spider-Man” has been confirmed for Seasons 2 and 3, it seems plausible that this story arc could develop in subsequent seasons.

A Major Spider-Verse Connection in ‘Your Friendly Neighborhood Spider-Man’

In the midst of Doctor Strange and Venom’s confrontation at Midtown High, a spider plummets through a celestial rift. This is the very same radioactive spider that transformed Peter Parker into Spider-Man. Interestingly, this spider’s arrival from another universe could make our friendly neighborhood Spider-Man an unusual case, much like Miles Morales in Spider-Man: Across the Spider-Verse.

In the movie “Spider-Man: Across the Spider-Verse,” it is revealed that the spider which bit Miles Morales didn’t originate from his dimension, but was brought in by the villain The Spot. This implies that Miles Morales as Spider-Man in these films wasn’t supposed to exist, and if the spider that bit Peter Parker in “Your Friendly Neighborhood Spider-Man” came from another dimension, it suggests that a different universe might be missing its own Spider-Man. If this is true, Miguel O’Hara would not have recruited the version of Peter Parker from “Your Friendly Neighborhood Spider-Man” into the Spider-Society.

In addition to this complication, if we’re dealing with a Marvel Cinematic Universe spin-off setting, it was intended for Peter Parker to be bitten by the spider. However, in this alternate timeline, he obtained his powers from a different spider around five to six months prior to the main MCU timeline. This means that the original spider that bit Peter Parker is still at large, as well as a spider from another universe that found its way into another student’s backpack. This scenario paves the way for Your Friendly Neighborhood Spider-Man to introduce additional web-slinging characters such as their own Gwen Stacy/Spider-Gwen, Cindy Moon / Silk, or even Miles Morales.

‘Your Friendly Neighborhood Spider-Man’ Opening Credits

The intro of Spider-Man: My Next-Door Pal is rich in subtle nods and connections to the broader Spider-Man universe lore. The theme song, “Neighbor Like Me” by The Math Club (featuring Relaye and Melo Makes Music), is a rap number that skillfully incorporates snippets from the iconic theme tune of the 1960s animated Spider-Man series by Paul Francis Webster and Bob Harris.

The song “Neighbor Like Me” includes the line “Extraordinary, supreme, he’s incredible,” which is a nod to the numerous Spider-Man comics and previous adaptations throughout the years.

  • The Amazing Spider-Man: First published in March 1963, it is Marvel’s flagship Spider-Man comic and inspired the name of Andrew Garfield’s Spider-Man franchise, The Amazing Spider-Man and The Amazing Spider-Man 2.
  • The Spectacular Spider-Man: The second ongoing Spider-Man title that has been used on and off by Marvel for many years. It was also the name of the popular short-lived animated series, The Spectacular Spider-Man, which many consider the best Spider-Man cartoon.
  • Ultimate Spider-Man: Launched in 2000, Ultimate Spider-Man reimagined the origin story of Peter Parker for the 21st century and was the comic that introduced Miles Morales. Marvel recently began publishing a new Ultimate Spider-Man comic title in 2023 that follows an adult, Peter Parker, who is married and has children. The name was also used for the 2012 to 2017 cartoon Ultimate Spider-Man, Disney’s first Spider-Man animated series.

The opening sequences of each installment in Your Friendly Neighborhood Spider-Man series mirrors classic Spider-Man comic covers, with episode 1, “Amazing Fantasy,” replicating the debut of Spider-Man as seen in The Amazing Spider-Man #15 from 1962.

Peter Parker’s Friends Range from Across the Marvel Universe

Since Midtown High was wrecked during Venom and Doctor Strange’s battle, Peter Parker now goes to Rockford High. As a result, he doesn’t encounter Ned Leeds or Michelle Jones (MJ) from the original MCU storyline. Instead, Peter has formed a new circle of friends, among whom is Nico Minoru, who he initially met during Midtown High’s orientation. Nico Minoru is a notable character in the Marvel Universe, being part of the teen superhero group, The Runaways. Co-created by writer Brian K. Vaughan and artist Adrian Alphona, she first appeared in Runaways #1 (July 2003). She’s one of six teens who uncover their parents as villains. Nico’s parents were dark wizards, granting her magical powers of her own. Previously, this version of Nico Minoru has been seen in the MCU-related series The Runaways, but she belongs to a separate character timeline within the Marvel multiverse.

The series shows us that Peter had a childhood crush on Pearl Pangan before attending Midtown High, who is now one of his schoolmates. In the Marvel Comics universe, Pearl Pangan is known as Wave, a Cebuano superheroine. Created by writer Greg Pak and artist Leinil Francis Yu, Wave first appeared in the comic book War of the Realms, New Agents of Atlas #1, published in May 2019, and she possesses water-based powers.

Pearl’s partner is Lonnie Lincoln, who comic book enthusiasts recognize as the antagonist Tombstone from Marvel Comics. Created by Gerry Conway and Alex Saviuk, this character debuted in “Web of Spider-Man” #36, published in March 1988. In the comics, Tombstone is depicted as an albino gangster, distinct from the one portrayed in “Your Friendly Neighborhood Spider-Man.” Unlike his comic book counterpart who was a contemporary of Peter Parker, this version of Tombstone is not yet established as a villain or friend to Peter. It’s intriguing to see if “Your Friendly Neighborhood Spider-Man” will follow the Marvel Cinematic Universe’s approach, where Ned Leeds, who adopted the Hobgoblin persona but had no evil intentions and became one of Peter Parker’s closest friends, is used instead. Alternatively, this could be a hint towards Lonnie Lincoln’s future development into Tombstone, a villain that Spider-Man will eventually have to confront.

In the first episode, we see Spider-Man rescuing a man from some thugs. This character is later identified as “Harry” but let me clarify, this Harry is none other than Harry Osborn, who in the comics is Peter Parker’s best friend and the son of Norman Osborn. You might remember Norman Osborn as the Green Goblin, and just like his father, Harry eventually adopts that villainous persona. Harry Osborn first appeared in The Amazing Spider-Man #31 in December 1965, created by Stan Lee and Steve Ditko. Previously, James Franco portrayed Harry Osborn in the Sam Raimi-directed Spider-Man trilogy, while Dane DeHaan took on the role in The Amazing Spider-Man 2. For now, we’ve only seen Harry Osborn in the first episode, but expect him to play a significant role as the series progresses.

Peter Working With Many Future Marvel Heroes and Villains

At OsCorp, when Peter Parker shows up, he encounters a variety of fresh faces among his intern peers and instructors. Among these are familiar names from the Marvel Universe, some dating back to the 1960s while others were introduced following the commencement of the Marvel Cinematic Universe. The interns with whom Peter works alongside include Jeanne Foucault, Amadeus Cho, and Asha.

  • Jeanne Foucault / Finesse was created by writer Christos Gage and artist Mike McKone and introduced in Avengers Academy #1 in June 2010. She is the daughter of Anthony Masters, who in the comics is the villain Taskmaster. Her powers are similar to Taskmasters in that she has photographic reflexes, which allow her to mimic any fighting style, but it comes at the cost of long and short-term memory.
  • Amadeus Cho was created by writer Greg Pak and Canadian artist Takeshi Miyazawa, and the character first appeared in Amazing Fantasy vol. 2 #15 in January 2005. Cho later became an established supporting player of Marvel heroes like The Hulk and Hercules. The Korean-American teenager is one of the smartest people in the Marvel Universe and, in 2015, became The Totally Awesome Hulk and later adopted the name Brawn after the original Hulk, Bruce Banner, returned from the dead. Cho will also appear in the upcoming Disney Jr. series Iron Man and His Amazing Friends as Iron Hulk.
  • Asha is a Wakanda exchange student. She was created by writer Matt Kindt and artist Steven Sanders and debuted in Infinity: The Hunt #1. In the comics, Asha attends the Wakandan School for Alternative Studies and develops the power to turn invisible and project light beam attacks.

It’s quite possible that these characters, who appear to be typical college students, could take on their superhero personas.

As opposed to Peter’s fellow science interns who may one day become Marvel superheroes, many researchers at OsCorp could turn into Marvel villains down the line. The first one Peter encounters is Bentley Whitman, infamous in the comics as ‘The Wizard.’ In the original story by Stan Lee and Larry Lieber, alongside artist Jack Kirby, The Wizard made his debut in Strange Tales #102 in November 1962. This character uses his scientific prowess, particularly in physics, to perpetrate crimes. Given that he’s already causing trouble for Peter Parker, it seems likely that Bentley Whitman will eventually transform into the villainous Wizard.

In the storyline, Peter Parker is given an internship under Dr. Carla Connors, who serves as a female counterpart of Curt Connors, famously known as The Lizard. The original Lizard character was co-created by Stan Lee and Steve Ditko and debuted in issue #6 of The Amazing Spider-Man back in November 1963. Given how nurturing Dr. Connors is towards Peter Parker during their brief interaction, it’s heartbreaking to think that she may eventually transform into The Lizard. Let’s hope Peter Parker can find a way to save her from this fate.

Including her character alongside Norman Osborn, the movie “Spider-Man: No Way Home” highlights the unique differences between Your Friendly Neighborhood Spider-Man and the Marvel Cinematic Universe (MCU). This is because in the MCU, Norman Osborn, Harry Osborn, and OsCorp don’t exist, nor has the MCU Peter Parker encountered The Lizard. However, both Tobey Maguire and Andrew Garfield’s Spider-Man had a Curt Conners in their respective universes. Currently, Your Friendly Neighborhood Spider-Man is available to stream on Disney+.

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2025-01-29 20:37